HKU5-CoV-2, a novel bat coronavirus found in China, shares similarities with SARS-CoV-2 and poses potential risks for human infection. Laboratory tests confirm its capacity to infect human cells effectively, although experts believe that current population immunity may reduce the pandemic risk. Further research is needed regarding the virus’s zoonotic potential and impact on humans.
A newly discovered bat coronavirus, termed HKU5-CoV-2, has been identified in China, raising concerns about its potential for animal-to-human transmission, akin to SARS-CoV-2, the virus responsible for the COVID-19 pandemic. This finding comes from a team of researchers led by Shi Zhengli, a prominent virologist at the Wuhan Institute, which has been scrutinized due to theories about the origins of COVID-19.
HKU5-CoV-2, part of the merbecovirus subgenus including MERS-CoV, has been shown to bind effectively to human ACE2 cells similarly to SARS-CoV-2. During laboratory experiments, scientists noted its ability to infect human cell cultures using mini-organ models designed for testing. The researchers highlighted that these bat-origin viruses pose a significant risk of spillover to humans, either directly or through intermediary species,
Despite the potential threats, Dr. Michael Osterholm from the University of Minnesota remarked that the public’s reaction to the possibility of another pandemic from this virus might be excessive. Current immunity levels in the population against related SARS viruses could mitigate the risk. The study has indicated HKU5-CoV-2 exhibits lower binding affinity to ACE2 compared to SARS-CoV-2, suggesting that while the risk exists, it should not be overstated.
The discovery of HKU5-CoV-2 highlights ongoing concerns about coronaviruses capable of zoonotic transmissions. While the potential for human infection exists, experts urge a balanced perspective, citing population immunity as a mitigating factor. Future investigations are necessary to fully understand the emergence and implications of this new virus.
Original Source: www.ndtv.com
